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This was followed by 3 focus groups (range 48 participants), and an individual interview with 1 participant who could not attend the focus groups, to understand participants rationales for their ratings and factors that influenced their perception of importance of outcomes (Appendix 3)

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Johns Wort and S-adenosyl-L-methionine.22 Other interventions No evidence on harms was identified for hypnotherapy, acupuncture, continuous auricular stimulation, laser therapy, or electrostimulation.22 E-cigarettes Fourteen RCTs27 31 , 33 , 34 , 36 , 37 , 39 , 45 48 and 1 cohort study49 provided data on e-cigarette harms, almost all at 36 months of follow-up